Total synthesis is the process of creating complex, naturally occurring molecules or compounds from simpler starting materials through a series of chemical reactions. This research area typically involves organic chemists who aim to reproduce the chemical structure and biological activity of a natural product in the lab. Total synthesis often requires innovative and creative approaches to overcome synthetic challenges and achieve the desired compound. It can provide valuable insights into the chemical reactivity and pathways of natural products, as well as potential applications in drug discovery, materials science, and other fields.